The protein kinase CK1: Inhibition, activation, and possible allosteric modulation

Protein kinases play a vital role in biology and deregulation of kinases is implicated in numerous diseases ranging from cancer to neurodegenerative diseases, making them a major target class for the pharmaceutical industry. However, the high degree of conservation that exists between ATP-binding si...

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Bibliographic Details
Main Authors: Yashoda Krishna Sunkari, Laurent Meijer, Marc Flajolet
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.916232/full