Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes
Abstract Background We performed expression quantitative trait locus (eQTL) analysis in single classical (CL) and non-classical (NCL) monocytes from patients with systemic lupus erythematosus (SLE) to quantify the impact of well-established genetic risk alleles on transcription at single-cell resolu...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-11-01
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Series: | Arthritis Research & Therapy |
Online Access: | https://doi.org/10.1186/s13075-021-02660-2 |