The relaxin family peptide receptor 1 (RXFP1): An emerging player in human health and disease

Abstract Background Relaxin/relaxin family peptide receptor 1 (RXFP1) signaling is important for both normal physiology and disease. Strong preclinical evidence supports relaxin as a potent antifibrotic molecule. However, relaxin‐based therapy failed in clinical trial in patients with systemic scler...

Full description

Bibliographic Details
Main Authors: Ting‐Yun Chen, Xiaoyun Li, Ching‐Hsia Hung, Harinath Bahudhanapati, Jiangning Tan, Daniel J. Kass, Yingze Zhang
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Online Access:https://doi.org/10.1002/mgg3.1194