IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission.

Invertebrates lack the immune machinery underlying vertebrate-like acquired immunity. However, in many insects past infection by the same pathogen can 'prime' the immune response, resulting in improved survival upon reinfection. Here, we investigated the mechanistic basis and epidemiologic...

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Bibliographic Details
Main Authors: Arun Prakash, Florence Fenner, Biswajit Shit, Tiina S Salminen, Katy M Monteith, Imroze Khan, Pedro F Vale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012308