An algorithm that predicts the viability and the yield of human hepatocytes isolated from remnant liver pieces obtained from liver resections.

Isolated human primary hepatocytes are an essential in vitro model for basic and clinical research. For successful application as a model, isolated hepatocytes need to have a good viability and be available in sufficient yield. Therefore, this study aims to identify donor characteristics, intra-oper...

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Bibliographic Details
Main Authors: Serene M L Lee, Celine Schelcher, Rüdiger P Laubender, Natalja Fröse, Reinhard M K Thasler, Tobias S Schiergens, Ulrich Mansmann, Wolfgang E Thasler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107567