Stereoselective synthesis of four possible isomers of streptopyrrolidine

Stereoselective synthesis of four possible isomers of streptopyrrolidine

The synthesis of (4R,5R)-streptopyrrolidine (1), (4S,5R)-streptopyrrolidine (2) (4R,5S)-streptopyrrolidine (3) and (4S,5S)-streptopyrrolidine (4) have been achieved in a concise and highly efficient manner via a highly stereoselective aldol type reaction with the trimethylsilyl enolate of ethyl acet...

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Bibliographic Details
Main Authors: Debendra K. Mohapatra, Barla Thirupathi, Pragna P. Das, Jhillu S. Yadav
Format: Article
Language:English
Published: Beilstein-Institut 2011-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
aldol reaction
angiogenesis
cancer
Lewis acid mediated lactamization
streptopyrrolidine
Online Access:https://doi.org/10.3762/bjoc.7.6

Internet

https://doi.org/10.3762/bjoc.7.6

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