Downregulation of MicroRNA-455-3p Links to Proliferation and Drug Resistance of Pancreatic Cancer Cells via Targeting TAZ

Downregulation of MicroRNA-455-3p Links to Proliferation and Drug Resistance of Pancreatic Cancer Cells via Targeting TAZ

Drug resistance is a major cause of treatment failure in pancreatic cancer. The limited evidence indicates the involvement of miR-455-3p in chemotherapy resistance of cancer. Here we observed by qPCR that miR-455-3p was significantly decreased in pancreatic cancer tissues and cell lines. We then con...

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Bibliographic Details
Main Authors: Ting Zhan, Xiaodong Huang, Xia Tian, Xiaoli Chen, Yu Ding, Hesheng Luo, Yadong Zhang
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miR-455-3p
TAZ
drug resistance
gemcitabine
pancreatic cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117303001

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http://www.sciencedirect.com/science/article/pii/S2162253117303001

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