Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in Adults.

A previously presented physiologically-based pharmacokinetic model for immediate release (IR) methylphenidate (MPH) was extended to characterize the pharmacokinetic behaviors of oral extended release (ER) MPH formulations in adults for the first time. Information on the anatomy and physiology of the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Xiaoxia Yang, John Duan, Jeffrey Fisher
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2016-01-01
श्रृंखला:PLoS ONE
ऑनलाइन पहुंच:http://europepmc.org/articles/PMC5056674?pdf=render