Erythropoietin re-wires cognition-associated transcriptional networks

Abstract Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely hematopoiesis-independent, but underlying mechanisms and physiological role of brain-expressed EPO remained obscure. Here, we provide transcriptional hippocampal profiling of male mice treated with rhEPO. Based...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Manvendra Singh, Ying Zhao, Vinicius Daguano Gastaldi, Sonja M. Wojcik, Yasmina Curto, Riki Kawaguchi, Ricardo M. Merino, Laura Fernandez Garcia-Agudo, Holger Taschenberger, Nils Brose, Daniel Geschwind, Klaus-Armin Nave, Hannelore Ehrenreich
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Nature Portfolio 2023-08-01
Цуврал:Nature Communications
Онлайн хандалт:https://doi.org/10.1038/s41467-023-40332-8