Technique integration of single-cell RNA sequencing with spatially resolved transcriptomics in the tumor microenvironment

Abstract Background The tumor microenvironment contributes to tumor initiation, growth, invasion, and metastasis. The tumor microenvironment is heterogeneous in cellular and acellular components, particularly structural features and their gene expression at the inter-and intra-tumor levels. Main tex...

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Bibliographic Details
Main Authors: Hailan Yan, Jinghua Shi, Yi Dai, Xiaoyan Li, Yushi Wu, Jing Zhang, Zhiyue Gu, Chenyu Zhang, Jinhua Leng
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02580-4