Optimal Weighted Multiple-Testing Procedure for Clinical Trials

Optimal Weighted Multiple-Testing Procedure for Clinical Trials

This paper describes a new method for testing randomized clinical trials with binary outcomes, which combines the O’Brien and Fleming (1979) multiple-testing procedure with optimal allocations and unequal weighted samples simultaneously. The O’Brien and Fleming method of group sequential testing is...

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Bibliographic Details
Main Authors: Hanan Hammouri, Marwan Alquran, Ruwa Abdel Muhsen, Jaser Altahat
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Mathematics
Subjects:
statistical algorithm
sequential group test
O’Brien and Fleming
Type I error and power
simulations
SAS software
Online Access:https://www.mdpi.com/2227-7390/10/12/1996

Internet

https://www.mdpi.com/2227-7390/10/12/1996

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