Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure

Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure

Abstract Heart failure (HF) patients in general have a higher risk of developing cancer. Several animal studies have indicated that cardiac remodeling and HF remarkably accelerate tumor progression, highlighting a cause-and-effect relationship between these two disease entities. Targeting ferroptosi...

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Bibliographic Details
Main Authors: Ye Yuan, Zhongting Mei, Zhezhe Qu, Guanghui Li, Shuting Yu, Yingqi Liu, Kuiwu Liu, Zhihua Shen, Jiaying Pu, Yanquan Wang, Changhao Wang, Zhiyong Sun, Qian Liu, Xiaochen Pang, Ao Wang, Zijing Ren, Tong Wang, Ying Liu, Jinhuan Hong, Jiajie Xie, Xin Li, Zhonghua Wang, Weijie Du, Baofeng Yang
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01336-4

Internet

https://doi.org/10.1038/s41392-023-01336-4

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