Serum free culture for the expansion and study of type 2 innate lymphoid cells

Abstract Type 2 innate lymphoid cells (ILC2s) were discovered approximately ten years ago and their clinical relevance is gaining greater importance. However, their successful isolation from mammalian tissues and in vitro culture and expansion continues to pose challenges. This is partly due to thei...

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Bibliographic Details
Main Authors: Pablo de Lucía Finkel, Christopher Sherwood, Iryna Saranchova, Wenjing Xia, Lonna Munro, Cheryl G. Pfeifer, James M. Piret, Wilfred A. Jefferies
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91500-z