ERK1/2-CEBPB Axis-Regulated hBD1 Enhances Anti-Tuberculosis Capacity in Alveolar Type II Epithelial Cells

ERK1/2-CEBPB Axis-Regulated hBD1 Enhances Anti-Tuberculosis Capacity in Alveolar Type II Epithelial Cells

Tuberculosis, caused by <i>Mycobacterium tuberculosis</i> (Mtb), remains a global health crisis with substantial morbidity and mortality rates. Type II alveolar epithelial cells (AEC-II) play a critical role in the pulmonary immune response against Mtb infection by secreting effector mol...

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Bibliographic Details
Main Authors: Yaoxin Chen, Zhenyu Han, Sian Zhang, Honglin Liu, Ke Wang, Jieyu Liu, Feichang Liu, Shiyun Yu, Na Sai, Haiyan Mai, Xinying Zhou, Chaoying Zhou, Qian Wen, Li Ma
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Mycobacterium tuberculosis</i>
alveolar type II epithelial cells
human β-defensin 1
CEBPB
Online Access:https://www.mdpi.com/1422-0067/25/4/2408

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https://www.mdpi.com/1422-0067/25/4/2408

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