Guianensin, a Simulium guianense salivary protein, has broad anti-hemostatic and anti-inflammatory properties

Guianensin, a Simulium guianense salivary protein, has broad anti-hemostatic and anti-inflammatory properties

BackgroundSalivary glands from blood-feeding arthropods secrete several molecules that inhibit mammalian hemostasis and facilitate blood feeding and pathogen transmission. The salivary functions from Simulium guianense, the main vector of Onchocerciasis in South America, remain largely understudied....

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Bibliographic Details
Main Authors: Paola Carolina Valenzuela-Leon, Andrezza Campos Chagas, Ines Martin-Martin, Adeline E. Williams, Markus Berger, Gaurav Shrivastava, Andrew S. Paige, Michalis Kotsyfakis, Lucas Tirloni, Eric Calvo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
blood feeding
black fly
saliva
arthropod
enzyme inhibitor
anticoagulant
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163367/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163367/full

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