One Size Does Not Fit All: Heterogeneity in Developmental Hematopoiesis

One Size Does Not Fit All: Heterogeneity in Developmental Hematopoiesis

Our knowledge of the complexity of the developing hematopoietic system has dramatically expanded over the course of the last few decades. We now know that, while hematopoietic stem cells (HSCs) firmly reside at the top of the adult hematopoietic hierarchy, multiple HSC-independent progenitor populat...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Cristiana Barone, Roberto Orsenigo, Raffaella Meneveri, Silvia Brunelli, Emanuele Azzoni
Format:	Artikel
Sprache:	English
Veröffentlicht:	MDPI AG 2022-03-01
Schriftenreihe:	Cells
Schlagworte:	hematopoiesis heterogeneity embryo hemogenic endothelium HSC EMP
Online Zugang:	https://www.mdpi.com/2073-4409/11/6/1061

Ähnliche Einträge

Signaling by Retinoic Acid in Embryonic and Adult Hematopoiesis
von: Elena Cano, et al.
Veröffentlicht: (2014-03-01)

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis
von: Rabab Nasrallah, et al.
Veröffentlicht: (2015-07-01)

Making Blood from the Vessel: Extrinsic and Environmental Cues Guiding the Endothelial-to-Hematopoietic Transition
von: Wade W. Sugden, et al.
Veröffentlicht: (2021-09-01)

CD1d expression demarcates CDX4+ hemogenic mesoderm with definitive hematopoietic potential
von: J. Philip Creamer, et al.
Veröffentlicht: (2022-07-01)

KIT Is Required for Fetal Liver Hematopoiesis
von: Alessandro Fantin, et al.
Veröffentlicht: (2021-07-01)

Lymphoid Tissue inducer (LTi) cell ontogeny and functioning in embryo and adult
von: Serge A. van de Pavert
Veröffentlicht: (2021-04-01)

Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis
von: Yang Li, et al.
Veröffentlicht: (2017-09-01)

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta
von: Lyad Zamir, et al.
Veröffentlicht: (2017-03-01)

A Bird’s Eye View on the Origin of Aortic Hemogenic Endothelial Cells
von: Pedro Seco, et al.
Veröffentlicht: (2020-11-01)

Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC
von: Ning Wang, et al.
Veröffentlicht: (2022-06-01)

Impact of viral infections on hematopoiesis: From beneficial to detrimental effects on bone marrow output.
von: Maria Fernanda Pascutti, et al.
Veröffentlicht: (2016-09-01)

Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos
von: Amanda D Yzaguirre, et al.
Veröffentlicht: (2015-10-01)

Unraveling the roles and mechanisms of mitochondrial translation in normal and malignant hematopoiesis
von: Lianxuan Liu, et al.
Veröffentlicht: (2024-10-01)

Location, Location, Location: How Vascular Specialization Influences Hematopoietic Fates During Development
von: Adam M. Heck, et al.
Veröffentlicht: (2020-11-01)

Mast Cell Repopulating Ability Is Lost During the Transition From Pre-HSC to FL HSC
von: Momoko Yoshimoto, et al.
Veröffentlicht: (2022-07-01)

Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor
von: Alejandra Vargas-Valderrama, et al.
Veröffentlicht: (2022-06-01)

From the niche to malignant hematopoiesis and back: reciprocal interactions between leukemia and the bone marrow microenvironment
von: Celia A. Soto, et al.
Veröffentlicht: (2021-10-01)

Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila
von: Nidhi Sharma Dey, et al.
Veröffentlicht: (2016-10-01)

NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice
von: Johannes Woelk, et al.
Veröffentlicht: (2025-01-01)

Hematopoietic Stem and Progenitor Cell Maintenance and Multiple Lineage Differentiation Is an Integral Function of NFATc1
von: Carlotta Barahona de Brito, et al.
Veröffentlicht: (2022-06-01)

Notch Signaling in HSC Emergence: When, Why and How
von: Roshana Thambyrajah, et al.
Veröffentlicht: (2022-01-01)

Cellular heterogeneity and clonal hematopoiesis of immune system cells in atherosclerosis
von: A. A. Sleptsov
Veröffentlicht: (2022-11-01)

Common in atherogenesis and carcinogenesis: clonal hematopoiesis
von: A. A. Sleptsov, et al.
Veröffentlicht: (2023-11-01)

Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence
von: Pankaj Sahai-Hernandez, et al.
Veröffentlicht: (2023-09-01)

Chicken anemia virus inhibits hematopoiesis and development of chicken embryo
von: Tianxing Yan, et al.
Veröffentlicht: (2025-04-01)

WNT5A from the fetal liver vascular niche supports human fetal liver hematopoiesis
von: Yoon Jung Choi, et al.
Veröffentlicht: (2021-06-01)

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification
von: Shailendra Maurya, et al.
Veröffentlicht: (2022-02-01)

Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture
von: Antoniana Batsivari, et al.
Veröffentlicht: (2017-06-01)

Emerging Insights into Molecular Mechanisms of Inflammation in Myelodysplastic Syndromes
von: Veronica Vallelonga, et al.
Veröffentlicht: (2023-09-01)

A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo
von: Gerel Melig, et al.
Veröffentlicht: (2023-08-01)

A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells
von: Keita Yamamoto, et al.
Veröffentlicht: (2021-08-01)

Absence of Nkx2-3 induces ectopic lymphatic endothelial differentiation associated with impaired extramedullary stress hematopoiesis in the spleen
von: Fanni Gábris, et al.
Veröffentlicht: (2023-04-01)

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis
von: Juliet R Girard, et al.
Veröffentlicht: (2021-10-01)

“Hierarchy” and “Holacracy”; A Paradigm of the Hematopoietic System
von: Takafumi Yokota
Veröffentlicht: (2019-09-01)

CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development
von: Anna Klaus, et al.
Veröffentlicht: (2022-06-01)

MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice
von: Jimmy L Zhao, et al.
Veröffentlicht: (2013-05-01)

Macrophages Orchestrate Hematopoietic Programs and Regulate HSC Function During Inflammatory Stress
von: Allison N. Seyfried, et al.
Veröffentlicht: (2020-07-01)

Pathogenesis of Cerebral Malaria: a combination of inflammation and cytoadherence?
von: Janet eStorm, et al.
Veröffentlicht: (2014-07-01)

Prenatal Origin of Pediatric Leukemia: Lessons From Hematopoietic Development
von: Anna Cazzola, et al.
Veröffentlicht: (2021-01-01)

Extramedullary hematopoiesis: A case report
von: Majda Ankri, et al.
Veröffentlicht: (2025-05-01)