Bioluminescence imaging allows monitoring hepatitis C virus core protein inhibitors in mice.

BACKGROUND: The development of small molecule inhibitors of hepatitis C virus (HCV) core protein as antiviral agents has been intensively pursued as a viable strategy to eradicate HCV infection. However, lack of a robust and convenient small animal model has hampered the assessment of in vivo effica...

Full description

Bibliographic Details
Main Authors: Juan Du, Fang Zhao, Yong Zhou, Hu Yan, Xiang-guo Duan, Sheng-qiang Liang, Ying-li Wang, Qiu-xia Fu, Xiao-hui Wang, Jian-chun Peng, Lin-sheng Zhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2987796?pdf=render