Regioselective Reduction of 1<i>H</i>-1,2,3-Triazole Diesters

Regioselective Reduction of 1<i>H</i>-1,2,3-Triazole Diesters

Regioselective reactions can play pivotal roles in synthetic organic chemistry. The reduction of several 1-substituted 1,2,3-triazole 4,5-diesters by sodium borohydride has been found to be regioselective, with the C(5) ester groups being more reactive towards reduction than the C(4) ester groups. T...

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Bibliographic Details
Main Authors: Christopher R. Butler, Justin Bendesky, Allen Milton Schoffstall
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
1<i>H</i>-1,2,3-triazole
1,3-dipolar cycloaddition
metal-catalyzed azide-alkyne cycloaddition (CuAAC)
regioselective reduction
borohydride reduction
electron density modeling
Online Access:https://www.mdpi.com/1420-3049/26/18/5589

Internet

https://www.mdpi.com/1420-3049/26/18/5589

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