The Aftermath of Long-Term Cigarette Smoking on Telomere Length and Mitochondrial DNA Copy Number in Human Cumulus Cells Prior to In Vitro Fertilization—A Pilot Study

The Aftermath of Long-Term Cigarette Smoking on Telomere Length and Mitochondrial DNA Copy Number in Human Cumulus Cells Prior to In Vitro Fertilization—A Pilot Study

Cigarette smoking among women of reproductive age is known to take a toll on systemic health and fertility potential by severely impacting ovarian tissues and cells, such as granulosa and cumulus cells (CCs). The purpose of this study was to determine the potential damage caused by tobacco smoke at...

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Bibliographic Details
Main Authors: Fani Konstantinidou, Maria Cristina Budani, Guya Diletta Marconi, Francesca Gonnella, Annalina Sarra, Oriana Trubiani, Liborio Stuppia, Gian Mario Tiboni, Valentina Gatta
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
cigarette smoke
telomere length
mitochondrial DNA copy number variation
oxidative stress
cumulus cells
gene expression
Online Access:https://www.mdpi.com/2076-3921/11/9/1841

Internet

https://www.mdpi.com/2076-3921/11/9/1841

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