Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk
Cardiac safety remains the leading cause of drug development discontinuation. We developed a human cardiomyocyte-based model that has the potential to provide a predictive preclinical approach for simultaneously predicting drug-induced inotropic and pro-arrhythmia risk.Methods: Adult human primary c...
Asıl Yazarlar: | , , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2017-12-01
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Seri Bilgileri: | Frontiers in Physiology |
Konular: | |
Online Erişim: | http://journal.frontiersin.org/article/10.3389/fphys.2017.01073/full |