Resveratrol directly suppresses proteolysis possibly via PKA/CREB signaling in denervated rat skeletal muscle

Resveratrol directly suppresses proteolysis possibly via PKA/CREB signaling in denervated rat skeletal muscle

Abstract Although there are reports that polyphenol resveratrol (Rsv) may cause muscle hypertrophy in basal conditions and attenuate muscle wasting in catabolic situations, its mechanism of action is still unclear. Our study evaluated the ex vivo effects of Rsv on protein metabolism and intracellula...

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Main Authors: IVANILDO I.S. JÚNIOR, GUSTAVO O. ZANETTI, TALES S. VIEIRA, FLÁVIA P. ALBUQUERQUE, DAYANE A. GOMES, SILVA PAULA-GOMES, RAFAEL R. VALENTIM, FLAVIA A. GRAÇA, ISIS C. KETTLHUT, LUIZ C.C. NAVEGANTES, DAWIT A.P. GONÇALVES, EDUARDO C. LIRA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2023-12-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Intracellular Signaling Pathways
Muscle atrophy and hypertrophy
Sciatic nerve resection
Polyphenol
Protein Metabolism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000500802&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000500802&tlng=en

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