Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis.
A genome wide association study (GWAS) typically results in a few highly significant 'hits' and a much larger set of suggestive signals ('near-hits'). The latter group are expected to be a mixture of true and false associations. One promising strategy to help separate these is to...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3083387?pdf=render |