Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases

Dysregulated Antibody, Natural Killer Cell and Immune Mediator Profiles in Autoimmune Thyroid Diseases

The pathogenesis of autoimmune thyroid diseases (AITD) is poorly understood and the association between different immune features and the germline variants involved in AITD are yet unclear. We previously observed systemic depletion of IgG core fucosylation and antennary α1,2 fucosylation in...

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Bibliographic Details
Main Authors: Tiphaine C. Martin, Kristina M. Illieva, Alessia Visconti, Michelle Beaumont, Steven J. Kiddle, Richard J. B. Dobson, Massimo Mangino, Ee Mun Lim, Marija Pezer, Claire J. Steves, Jordana T. Bell, Scott G. Wilson, Gordan Lauc, Mario Roederer, John P. Walsh, Tim D. Spector, Sophia N. Karagiannis
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
multi-omic
autoimmune thyroid diseases (aitd)
genetic variants
apoptosis
antibody-dependent cell-mediated cytotoxicity (adcc)
anti-thyroid peroxidase antibody (tpoab)
Online Access:https://www.mdpi.com/2073-4409/9/3/665

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https://www.mdpi.com/2073-4409/9/3/665

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