Cellular senescence is associated with osteonecrosis of the femoral head while mesenchymal stem cell conditioned medium inhibits bone collapse

Abstract Osteonecrosis of the femoral head (ONFH) is a type of ischemic osteonecrosis that causes pain, loss of function, and femoral head collapse. Here, we analyzed samples of femoral heads excised from patients with ONFH to clarify the relationship between ischemic osteonecrosis and cellular sene...

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Bibliographic Details
Main Authors: Masanori Okamoto, Hiroaki Nakashima, Kiyoshi Sakai, Yasuhiko Takegami, Yusuke Osawa, Junna Watanabe, Sadayuki Ito, Hideharu Hibi, Shiro Imagama
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53400-w