Cellular senescence is associated with osteonecrosis of the femoral head while mesenchymal stem cell conditioned medium inhibits bone collapse
Abstract Osteonecrosis of the femoral head (ONFH) is a type of ischemic osteonecrosis that causes pain, loss of function, and femoral head collapse. Here, we analyzed samples of femoral heads excised from patients with ONFH to clarify the relationship between ischemic osteonecrosis and cellular sene...
Main Authors: | Masanori Okamoto, Hiroaki Nakashima, Kiyoshi Sakai, Yasuhiko Takegami, Yusuke Osawa, Junna Watanabe, Sadayuki Ito, Hideharu Hibi, Shiro Imagama |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-53400-w |
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