Ablation of the gut microbiota alleviates high-methionine diet-induced hyperhomocysteinemia and glucose intolerance in mice

Abstract A high-methionine (HM) diet leads to hyperhomocysteinemia (HHcy), while gastrointestinal tissue is an important site of net homocysteine (Hcy) production. However, the role of the gut microbiota in host HHcy remains obscure. This study aimed to determine whether gut microbiota ablation coul...

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Bibliographic Details
Main Authors: Wenqiang Li, Yiting Jia, Ze Gong, Zhao Dong, Fang Yu, Yi Fu, Changtao Jiang, Wei Kong
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-023-00212-3