A Novel Mechanism for Bone Loss: Platelet Count Negatively Correlates with Bone Mineral Density via Megakaryocyte-Derived RANKL

A Novel Mechanism for Bone Loss: Platelet Count Negatively Correlates with Bone Mineral Density via Megakaryocyte-Derived RANKL

A potential association between hematopoietic stem cell status in bone marrow and surrounding bone tissue has been hypothesized, and some studies have investigated the link between blood count and bone mineral density (BMD), although their exact relationship remains controversial. Moreover, biologic...

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Bibliographic Details
Main Authors: Shohei Kikuchi, Akinori Wada, Yusuke Kamihara, Imari Yamamoto, Daiki Kirigaya, Kohei Kunimoto, Ryusuke Horaguchi, Takuma Fujihira, Yoshimi Nabe, Tomoki Minemura, Nam H. Dang, Tsutomu Sato
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
platelet
bone mineral density
megakaryocyte
RANKL
Online Access:https://www.mdpi.com/1422-0067/24/15/12150

Internet

https://www.mdpi.com/1422-0067/24/15/12150

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