An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis.

An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis.

Striking individual differences in severity of group A streptococcal (GAS) sepsis have been noted, even among patients infected with the same bacterial strain. We had provided evidence that HLA class II allelic variation contributes significantly to differences in systemic disease severity by modula...

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Bibliographic Details
Main Authors: Nourtan F Abdeltawab, Ramy K Aziz, Rita Kansal, Sarah L Rowe, Yin Su, Lidia Gardner, Charity Brannen, Mohammed M Nooh, Ramy R Attia, Hossam A Abdelsamed, William L Taylor, Lu Lu, Robert W Williams, Malak Kotb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2277464?pdf=render

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http://europepmc.org/articles/PMC2277464?pdf=render

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