HNPCC <it>versus </it>sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression

HNPCC <it>versus </it>sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression

<p>Abstract</p> <p>Background</p> <p>Abnormalities in Human Leukocyte Antigen (HLA) class I expression are common in colorectal cancer. Since HLA expression is required to activate tumor antigen-specific cytotoxic T-lymphocytes (CTL), HLA class I abnormalities represent...

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Bibliographic Details
Main Authors: Fleuren Gert, Cornelisse Cees J, van Puijenbroek Marjo, Ferrone Soldano, de Miranda Noel FCC, Dierssen Jan, van Wezel Tom, Morreau Hans
Format: Article
Language:English
Published: BMC 2007-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/33

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http://www.biomedcentral.com/1471-2407/7/33

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