Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate[S]

Extracellular lysophosphatidate and sphingosine 1-phosphate (S1P) are important bioactive lipids, which signal through G-protein-coupled receptors to stimulate cell growth and survival. The lysophosphatidate and S1P signals are terminated partly by degradation through three broad-specificity lipid p...

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Bibliographic Details
Main Authors: Xiaoyun Tang, Yuan Y. Zhao, Jay Dewald, Jonathan M. Curtis, David N. Brindley
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354158