Signature of miRNAs derived from the circulating exosomes of patients with amyotrophic lateral sclerosis

Signature of miRNAs derived from the circulating exosomes of patients with amyotrophic lateral sclerosis

BackgroundAmyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disorder (NDS) with unclear pathophysiology and few therapeutic options. Mutations in SOD1 and C9orf72 are the most common in Asian and Caucasian patients with ALS, respectively. Aberrant (microRNAs) miRNAs found...

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Bibliographic Details
Main Authors: Yang-Fan Cheng, Xiao-Jing Gu, Tian-Mi Yang, Qian-Qian Wei, Bei Cao, Yang Zhang, Hui-Fang Shang, Yong-Ping Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
amyotrophic lateral sclerosis
microRNAs
exosomes
gene mutation
diagnostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1106497/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1106497/full

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