Longitudinal transcriptomic analysis of mouse sciatic nerve reveals pathways associated with age‐related muscle pathology

Longitudinal transcriptomic analysis of mouse sciatic nerve reveals pathways associated with age‐related muscle pathology

Abstract Background Sarcopenia, the age‐associated decline in skeletal muscle mass and strength, has long been considered a disease of muscle only, but accumulating evidence suggests that sarcopenia could originate from the neural components controlling muscles. To identify early molecular changes i...

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Bibliographic Details
Main Authors: Nicole Comfort, Meethila Gade, Madeleine Strait, Samantha J. Merwin, Daphne Antoniou, Chiara Parodi, Lina Marcinczyk, Lea Jean‐Francois, Tessa R. Bloomquist, Anna Memou, Hardy J. Rideout, Stefania Corti, Shingo Kariya, Diane B. Re
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
aging
frailty
motor unit
RNA‐seq
sarcopenia
skeletal muscle
Online Access:https://doi.org/10.1002/jcsm.13204

Internet

https://doi.org/10.1002/jcsm.13204

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