Multiplex Capillary Denaturing High-Performance Liquid Chromatography with Laser-Induced Fluorescence Detection
Denaturing high-performance liquid chromatography (DHPLC) is a sensitive, robust, and operationally inexpensive method for the detection of single-base substitutions and small deletions and insertions. To increase sample throughput, we have developed a multiplexing strategy using fluorophores to dis...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2001-06-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/01306rr01 |