Uncertainty Evaluation for the Quantification of Urinary Amphetamine and 4-Hydroxyamphetamine Using Liquid Chromatography–Tandem Mass Spectrometry: Comparison of the Guide to the Expression of Uncertainty in Measurement Approach and the Monte Carlo Method with R

Uncertainty Evaluation for the Quantification of Urinary Amphetamine and 4-Hydroxyamphetamine Using Liquid Chromatography–Tandem Mass Spectrometry: Comparison of the Guide to the Expression of Uncertainty in Measurement Approach and the Monte Carlo Method with R

Estimating the measurement uncertainty (MU) is becoming increasingly mandatory in analytical toxicology. This study evaluates the uncertainty in the quantitative determination of urinary amphetamine (AP) and 4-hydroxyamphetamine (4HA) using a liquid chromatography–tandem mass spectrometry (LC–MS/MS)...

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Bibliographic Details
Main Authors: Seon Yeong Kim, Dong Won Shin, Jihye Hyun, Nam Hee Kwon, Jae Chul Cheong, Ki-Jung Paeng, Jooyoung Lee, Jin Young Kim
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
measurement uncertainty
Guide to the Expression of Uncertainty in Measurement
Monte Carlo method
amphetamine
LC–MS/MS
Online Access:https://www.mdpi.com/1420-3049/28/19/6803

Internet

https://www.mdpi.com/1420-3049/28/19/6803

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