Pharmacokinetics of a liposomal formulation of doxorubicin in rats

Background: Measuring free drug concentration following systemic administration of a liposomal drug is a crucial aspect of the assessment of its in vivo behavior. Therefore we require an efficient method to separate free drug in the plasma from encapsulated drug. Objectives: To study the pharmacokin...

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Bibliographic Details
Main Authors: Zongyu Liu, Ye Bi, Yating Sun, Fei Hao, Jiahui Lu, Qingfan Meng, Robert J. Lee, Yaping Tian, Jing Xie
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S131901641730083X