Gene editing for latent herpes simplex virus infection reduces viral load and shedding in vivo
Abstract Anti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic neurons, the source of recurrent disease. We have developed a potentially curative approach against HSV infection, based on gene editing using HSV-specific meganucleases delivered by adeno...
| Main Authors: | , , , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Nature Portfolio
2024-05-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/s41467-024-47940-y |