Molecular mechanisms underlying hyperoxia-induced lung fibrosis

Supplemental oxygen is often used to treat newborns with respiratory disorders. Exposure to high concentration of oxygen and long-term oxygen causes inflammation and acute lung injury. The acute inflammatory phase is followed by a fibroproliferative repair phase, leading to lung fibrosis. Many infan...

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Bibliographic Details
Main Authors: I-Ting Chen, Liang-Ti Huang, Chih-Cheng Chen, Chung-Ming Chen
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957222000092