Molecular evolution of human coronavirus-NL63, -229E, -HKU1 and -OC43 in hospitalized children in China

Molecular evolution of human coronavirus-NL63, -229E, -HKU1 and -OC43 in hospitalized children in China

Human coronaviruses (HCoVs) HCoV-NL63, HCoV-229E, HCoV-HKU1 and HCoV-OC43 have been circulated in the human population worldwide, and they are associated with a broad range of respiratory diseases with varying severity. However, there are neither effective therapeutic drugs nor licensed vaccines ava...

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Bibliographic Details
Main Authors: Nan Shao, Chi Zhang, Jie Dong, Lilian Sun, Xiangpeng Chen, Zhengde Xie, Baoping Xu, Shuhua An, Ting Zhang, Fan Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
human coronavirus
spike gene
phylogenetic analysis
recombination analysis
N-glycosylation site
amino acid site
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1023847/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1023847/full

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