HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway

Laryngeal squamous cell carcinoma (LSCC) is an aggressive and lethal malignant neoplasm with extremely poor prognoses. Accumulating evidence has indicated that preferentially expressed antigen in melanoma (PRAME) is correlated with several kinds of cancers. However, there is little direct evidence t...

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Bibliographic Details
Main Authors: Yu Lei, Cao Huan, Yang Jian-Wang, Meng Wen-Xia, Yang Chuan, Wang Jian-Tao, Yu Miao-Miao, Wang Bao-Shan
Format: Article
Language:English
Published: De Gruyter 2023-03-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0665