TMED3 promotes the development of malignant melanoma by targeting CDCA8 and regulating PI3K/Akt pathway

Abstract Background Transmembrane emp24 domain containing (TMED) proteins are known to play pivotal roles in normal development, but have been reported to be implicated in pancreatic disease, immune system disorders, and cancers. As far as TMED3 is concerned, its roles in cancers are controversial....

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Bibliographic Details
Main Authors: Xianling Guo, Xiaolan Yin, Yu Xu, Liang Li, Min Yuan, Huaxin Zhao, Yuxiong Jiang, Xiujuan Shi, Hongda Bi, Yeqiang Liu, Yong Chen, Qing Xu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-023-01006-6