Green Synthesis and Anticancer Potential of 1,4-Dihydropyridines-Based Triazole Derivatives: In Silico and In Vitro Study

Green Synthesis and Anticancer Potential of 1,4-Dihydropyridines-Based Triazole Derivatives: In Silico and In Vitro Study

A library of 1,4-dihydropyridine-based 1,2,3-triazol derivatives has been designed, synthesized, and evaluated their cytotoxic potential on colorectal adenocarcinoma (Caco-2) cell lines. All compounds were characterized and identified based on their <sup>1</sup>H and <sup>13</su...

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Bibliographic Details
Main Authors: Sabera Bijani, Danish Iqbal, Sheefa Mirza, Vicky Jain, Sadaf Jahan, Mohammed Alsaweed, Yahya Madkhali, Suliman A. Alsagaby, Saeed Banawas, Abdulrahman Algarni, Faris Alrumaihi, Rakesh M. Rawal, Wael Alturaiki, Anamik Shah
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Life
Subjects:
click chemistry
green synthesis
cytotoxicity
apoptosis
cheminformatics
protein kinase
Online Access:https://www.mdpi.com/2075-1729/12/4/519

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https://www.mdpi.com/2075-1729/12/4/519

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