Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes

Exposure of human peripheral blood monocytes to free arachidonic acid (AA) results in the rapid induction of lipid droplet (LD) formation by these cells. This effect appears specific for AA in that it is not mimicked by other fatty acids, whether saturated or unsaturated. LDs are formed by two diffe...

Full description

Bibliographic Details
Main Authors: Carlos Guijas, Gema Pérez-Chacón, Alma M. Astudillo, Julio M. Rubio, Luis Gil-de-Gómez, María A. Balboa, Jesús Balsinde
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412519