The Epigenome of Schistosoma mansoni Provides Insight about How Cercariae Poise Transcription until Infection.

BACKGROUND:Chromatin structure can control gene expression and can define specific transcription states. For example, bivalent methylation of histone H3K4 and H3K27 is linked to poised transcription in vertebrate embryonic stem cells (ESC). It allows them to rapidly engage specific developmental pat...

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Bibliographic Details
Main Authors: David Roquis, Julie M J Lepesant, Marion A L Picard, Michael Freitag, Hugues Parrinello, Marco Groth, Rémi Emans, Céline Cosseau, Christoph Grunau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4549315?pdf=render