Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

Abstract Background Bile acids (BAs) are steroid-derived molecules with important roles in digestion, the maintenance of host metabolism, and immunomodulation. Primary BAs are synthesized by the host, while secondary BAs are produced by the gut microbiome through transformation of the former. The re...

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Bibliographic Details
Main Authors: Eduard Vico-Oton, Colin Volet, Nicolas Jacquemin, Yuan Dong, Siegfried Hapfelmeier, Karin Lederballe Meibom, Rizlan Bernier-Latmani
Format: Article
Language:English
Published: BMC 2024-08-01
Series:BMC Microbiology
Subjects:
7-dehydroxylation
Clostridium scindens
Extibacter muris
Gut microbiome
Deoxycholic acid (DCA)
Lithocholic acid (LCA)
Online Access:https://doi.org/10.1186/s12866-024-03433-y

Internet

https://doi.org/10.1186/s12866-024-03433-y

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