Further investigation of blockade effects and binding affinities of selected natural compounds to immune checkpoint PD-1/PD-L1

The breakthrough in the discovery of immune checkpoint PD-1/PD-L1 inhibitors, such as the series of Bristol Myers Squibb synthetic compounds, boosted the research of small molecules with blockade effects on the interaction of PD-1/PD-L1. However, the search for natural products derived PD-1/PD-L1 in...

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Bibliographic Details
Main Authors: Huifang Li, Navindra P. Seeram, Chang Liu, Hang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.995461/full