Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells

Abstract.: We evaluated the effect of alacepril, CV-11974, and spironolactone on the production of monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-alpha (TNF-α) in cultured human peripheral blood mononuclear cells stimulated with angiotensin (Ang) II. Alacepril, CV-11974, and sp...

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Main Authors: Miura Ryuzea, Nakamura Kazufumi, Miura Daiji, Miura Aya, Hisamatsu Kenichi, Kajiya Masahito, Nagase Satoshi, Morita Hiroshi, Kusano Kengo Fukushima, Ohe Tohru, Ishihara Kazuhiko
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344536