Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS

Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS

Abstract The bactericidal activity of several antibiotics partially relies on the production of reactive oxygen species (ROS), which is generally linked to enhanced respiration and requires the Fenton reaction. Bacterial persister cells, an important cause of recurring infections, are tolerant to th...

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Bibliographic Details
Main Authors: Declan A. Gray, Biwen Wang, Margareth Sidarta, Fabián A. Cornejo, Jurian Wijnheijmer, Rupa Rani, Pamela Gamba, Kürşad Turgay, Michaela Wenzel, Henrik Strahl, Leendert W. Hamoen
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51347-0

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https://doi.org/10.1038/s41467-024-51347-0

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