Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease.

Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease.

The apolipoprotein E gene (APOE) is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), yet the expression of APOE is not clearly understood. For example, it is unclear whether AD patients have elevated or decreased APOE expression or why the correlation levels of APOE RN...

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Bibliographic Details
Main Authors: Eun-Gyung Lee, Jessica Tulloch, Sunny Chen, Lesley Leong, Aleen D Saxton, Brian Kraemer, Martin Darvas, C Dirk Keene, Andrew Shutes-David, Kaitlin Todd, Steve Millard, Chang-En Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227667

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https://doi.org/10.1371/journal.pone.0227667

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