Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation.

Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation.

Maintaining genome integrity is particularly important in germ cells to ensure faithful transmission of genetic information across generations. Here we systematically describe germ cell mutagenesis in wild-type and 61 DNA repair mutants cultivated over multiple generations. ~44% of the DNA repair mu...

Full description

Bibliographic Details
Main Authors: Bettina Meier, Nadezda V Volkova, Ye Hong, Simone Bertolini, Víctor González-Huici, Tsvetana Petrova, Simon Boulton, Peter J Campbell, Moritz Gerstung, Anton Gartner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0250291

Internet

https://doi.org/10.1371/journal.pone.0250291

Similar Items