Post-translational modifications to hemidesmosomes in human airway epithelial cells following diacetyl exposure

Abstract Diacetyl (DA; 2,3-butanedione) is a highly reactive alpha (α)-diketone. Inhalation exposure to DA can cause significant airway epithelial cell injury, however, the mechanisms of toxicity remain poorly understood. The purpose of these experiments was to assess for changes in abundance and di...

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Bibliographic Details
Main Authors: So-Young Kim, Matthew D. McGraw
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14019-x